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  Nuclear Medicine


 

 

Nuclear Medicine is a discipline in medical radiation technology. It involves the use of radioactive substances and radiation technology to help diagnose, and, in some cases, treat medical problems.

Nuclear Medicine procedures are divided into two parts, laboratory work and imaging (scanning). The lab prepares radioactive solutions (radiopharmaceuticals) for intravenous injection. The radioactive solutions allow the specialized imaging equipment (gamma cameras) to acquire images. Computer programs process the information obtained from the images, in order to determine the location, size, and function of body tissues and organs. The type of radioactive tracer solution used is different for different parts of the body.

     

Patients rarely suffer side effects from the intravenous injection used in Nuclear Medicine procedures and feel nothing from the radioactive solution, or the scanning procedure. Patients receive less radiation than from many x-ray procedures. However, since some radiation is involved, the Department will not perform tests on pregnant women. If there is a possibility of pregnancy, a pregnancy test is required prior to performing the Nuclear Medicine procedure. Breast-feeding mothers are required to stop two to four days prior to having a Nuclear Medicine procedure.


 

 

 

 

 

 

 

 

 

 

During nuclear medicine examination, radioactively labeled material, a radiopharmaceutical, is injected, for example, into the veins of a patient. The choice of the material depends on the type of examination one wants to perform. For examining thyroid disorders, an iodine compound that is taken up by the thyroid can be used, whereas in vessel examinations, erythrocytes labeled with radioactive technetium are applied. The radiopharmaceutical (the carrier of the isotope) is chosen in such a way that this compound is preferably absorbed by the organ we are interested in. Its radiation is then used to create an image. The radiation emitted by the isotopes is partly absorbed inside the patient, and the remainder is detected by a so-called gamma camera. The gamma camera is usually connected to a computer system, with which it is then possible to construct an image.

Radioactive isotopes disintegrate into stable isotopes. For medical examinations it is better to use an isotopes with a relatively short half-life, which is the time in which the activity is reduced by 50%, to limit to a minimum the amount of radiation to which a patient is exposed. The radioactive isotopes with short half-lives are produced in so-called generators, that contain radioactive material with a relatively long half-life that decays into the requested isotope. Over a number of days, the generator is used to produce the radioactive material needed for imaging. A technetium generator, for example, contains the radioactive isotope molybdenum-99, which has a half-life of 67 hours. This isotope disintegrates to Technetium-99m, which has a half-life of 6 hours. The latter isotope is used for imaging purposes.
 

   

Nuclear medicine specialists use safe, painless, and cost-effective techniques to image the body and treat disease. Nuclear medicine imaging is unique, because it provides doctors with information about both structure and function. It is a way to gather medical information that would otherwise be unavailable, require surgery, or necessitate more expensive diagnostic tests.

Nuclear medicine imaging procedures often identify abnormalities very early in the progress of a disease—long before many medical problems are apparent with other diagnostic tests. Nuclear medicine uses very small amounts of radioactive materials (radiopharmaceuticals) to diagnose and treat disease. In imaging, the radiopharmaceuticals are detected by special types of cameras that work with computers to provide very precise pictures about the area of the body being imaged. In treatment, the radiopharmaceuticals go directly to the organ being treated. The amount of radiation in a typical nuclear imaging procedure is comparable with that received during a diagnostic x-ray, and the amount received in a typical treatment procedure is kept within safe limits.

Today, nuclear medicine offers procedures that are essential in many medical specialties, from pediatrics to cardiology to psychiatry. New and innovative nuclear medicine treatments that target and pinpoint molecular levels within the body are revolutionizing our understanding of and approach to a range of diseases and conditions.

 

 

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